Wash and dry your basil leaves.
Grate a block of grana padano cheese using a fine grater. You should make at least one cup, but feel free to add more for extra cheesiness.
For a creamier pesto, blend pistachios with olive oil first, then add basil and cheese. For a chunkier texture, pulse basil leaves and oil first, but not longer than ten seconds.
Add the grated cheese and pulse until fully combined. Keep adding more olive oil if needed for consistency.
Scrape the sides of the bowl, add pistachios, and pulse a few more times.
Mix in lemon juice, lemon zest, salt, and pepper to taste.
Transfer to a bowl or jar, mix it with pasta or use it for your favorite dish. Enjoy!